{"product_id":"sam-e-400-mg","title":"Osterly Market SAM-e 400 mg","description":"\u003cp class=\"osm-front\"\u003e\u003cstrong\u003e400 mg SAM-e. Enteric coated.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFour hundred milligrams of SAM-e in an enteric-coated tablet — a coating this compound genuinely needs and often does not get.\u003c\/p\u003e\u003ch4\u003eWhat it's for\u003c\/h4\u003e\u003cp\u003eSAM-e is a molecule your body makes from methionine and ATP, involved in methylation reactions throughout the body. It is taken for joint comfort and for mood, and it has more human trial data behind it than most ingredients in this category.\u003c\/p\u003e\u003ch4\u003eHow to take it\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eOne tablet daily on an empty stomach, ideally in the morning\u003c\/li\u003e\n\u003cli\u003eFood reduces absorption, so time it away from meals\u003c\/li\u003e\n\u003cli\u003eJoint effects generally take three to four weeks; mood effects have shown faster in trials\u003c\/li\u003e\n\u003cli\u003eThis one has real interactions. Do not combine it with antidepressants, and speak to a doctor first if you have bipolar disorder — SAM-e has triggered mania in some cases\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eOn the label\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003e400 mg per tablet\u003c\/li\u003e\n\u003cli\u003eEnteric coated\u003c\/li\u003e\n\u003cli\u003e60 tablets\u003c\/li\u003e\n\u003cli\u003eSingle ingredient\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eWhat this is not\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eNot an antidepressant\u003c\/li\u003e\n\u003cli\u003eNot to be combined with SSRIs without medical advice\u003c\/li\u003e\n\u003cli\u003eNot effective uncoated, which is why the coating is on the label\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eThe straight answer\u003c\/h4\u003e\u003cp\u003eUncoated SAM-e is largely destroyed by stomach acid. If a SAM-e product does not say 'enteric coated' anywhere, that omission is the most informative thing on the bottle.\u003c\/p\u003e\u003chr\u003e\u003cp\u003e\u003csmall\u003eFree shipping on every order, no minimum. Questions or a complaint about shipping or a product? Email us and a person will answer.\u003c\/small\u003e\u003c\/p\u003e\u003cp\u003e\u003csmall\u003eThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Talk to your doctor before starting any supplement, especially if you are pregnant, nursing, or taking prescription medication.\u003c\/small\u003e\u003c\/p\u003e","brand":"Osterly Market","offers":[{"title":"60 tablets","offer_id":49636595597539,"sku":"OSM-N111","price":23.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0815\/0096\/3043\/files\/Se22df7c69686442ea2585cda646f7cbfv.webp?v=1788012359","url":"https:\/\/osterly.us\/products\/sam-e-400-mg","provider":"Osterly Market","version":"1.0","type":"link"}